Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety, Patient Safety in Surgery
Por um escritor misterioso
Last updated 15 junho 2024
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Incremental doses of intravenous labetalol are safe and effective and, at times, such therapy may need to be augmented by a continuous infusion of labetalol to control severe hypertension. Continuous infusions of labetalol may exceed the recommended maximum daily dose of 300 mg on occasion. We report a case in which hypertension occurring after an abdominal aortic aneurysm repair, initially responsive to intermittent intravenous beta-blockade, became resistant to this therapy leading to the choice of an intravenous labetalol infusion as the therapeutic option. The labetalol infusion resulted in a profound cardiovascular compromise in this postoperative critically ill patient. While infusions of labetalol have successfully been used, prolonged administration in the intensive care unit requires vigilance and the establishment of a therapeutic rationale/policy for interventions, such as the ready availability of glucagon, β-agonists, phosphodiesterase inhibitors, insulin, and vasopressin when severe cardiovascular depression occurs.
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PDF) Safety and efficacy of continuous intravenous labetalol for blood pressure control in neurosurgical patients
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Labetalol: Package Insert
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Frontiers Beta-Adrenergic Blockade in Critical Illness
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Hemodynamic Safety of Continuous Infusion Labetalol Versus Esmolol Combination Therapies for Type B Aortic Dissections
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Management of Women With Acquired Cardiovascular Disease From Pre-Conception Through Pregnancy and Postpartum: JACC Focus Seminar 3/5 - ScienceDirect
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LABETALOL HYDROCHLORIDE injection
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Use of Medication for Cardiovascular Disease During Pregnancy: JACC State-of-the-Art Review
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Carvedilol Among Patients With Heart Failure With a Cocaine-Use Disorder
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Comparing Labetalol and Nitroglycerine on Inducing Controlled Hypotension and Intraoperative Blood Loss in Rhinoplasty: A Single-Blinded Clinical Trial, Anesthesiology and Pain Medicine
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PDF] Managing Hypertension in Patients With Stroke Are You Prepared for Labetalol Infusion
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LABETALOL HYDROCHLORIDE tablet, film coated
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Full article: Remifentanil versus labetalol for deliberate hypotensive anesthesia in children undergoing cochlear implantation: A randomized clinical trial
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